Medical Field: Pulmonology and Allergology
Award: Finalist
Country: Serbia
Year: 2024
Research Work: Asthma Inflammatory Phenotypes: How Can We Distinguish Them?
Published in: Journal of Clinical Medicine

Being a doctor is a great responsibility; it means having the opportunity to make a difference in people's everyday lives.

 

Aleksandra Plavšić, MD, PhD, is currently working as an Allergist and Clinical immunologist at the Clinic for Allergy and Immunology, University Clinical Centre of Serbia. She is also an Assistant Professor of Internal medicine, at the Faculty of Medicine University of Belgrade, Serbia. 

Dr. Aleksandra Plavšić is an Allergist and Clinical Immunologist at the Clinic for Allergy and Immunology, University Clinical Centre of Serbia, and an Assistant Professor in Internal Medicine at the Faculty of Medicine, University of Belgrade. With 20 years of experience, she has been dedicated to treating patients with a wide spectrum of immunological and allergic disorders. Her areas of expertise include systemic lupus erythematosus, antiphospholipid syndrome, systemic vasculitis, reproductive immunology, chronic urticaria and asthma. Dr. Plavšić’s research focuses on identifying asthma phenotypes by evaluating unique patient characteristics and inflammation types to provide personalized treatment.
 

Personalized approaches in asthma therapy

Dr. Aleksandra Plavšić’s research focuses on identifying asthma phenotypes to better understand unique patient characteristics and the type of inflammation present. This approach is essential for tailoring the most effective therapy for each individual. Her work highlights the importance of a personalized approach in clinical practice. By using induced sputum and biomarkers—such as blood leukocytes, neutrophils, eosinophils, IL-17A, IL-5, IL-6, and IL-8—her study aims to distinguish between different asthma inflammatory phenotypes, which is crucial for optimizing treatment strategies.

In this study, the authors evaluated the proportion and characteristics of asthma phenotypes in a patient cohort using induced sputum analysis. The cohort included patients with varying levels of asthma control, inhalation therapies, and biological treatments. Clinically relevant differences in inflammatory markers were identified between patient groups, providing valuable insights into asthma pathobiology and treatment response. This research makes an important contribution to the field of asthma phenotyping and personalized medicine.
 

A lifelong commitment to healing and human connection

For Dr. Aleksandra Plavšić, medicine is not just a career, but an integral part of her life. With over 20 years of experience, she finds fulfillment in the privilege of helping people through their health challenges. Her passion for medicine extends beyond clinical practice; it is rooted in the desire to make a meaningful difference in her patients' lives. Whether as a doctor, wife, mother, daughter, aunt or friend, Dr. Plavšić’s roles shape her world and fuel her commitment to her work. 

She draws inspiration from the emotional connections with her patients and the lessons they impart, understanding that sometimes a simple gesture of care can have the most profound impact. Through her work, she aims to bring not only scientific expertise but also empathy and humanity into her patient care.